The science behind Formula C
Formula C has been clinically shown to alleviate Long COVID symptoms. Get an in-depth view of the science and pathophysiology behind Formula C and how it helps to alleviate Long COVID symptoms.
January 26, 2024
For those of you who have been dealing with Long COVID for a long time, you know there is no one stop solution to Long COVID and that it’s about building a personal protocol that works for you.
Unlike many other products on the market, Formula C has actually been studied in Long COVID patients. Study results were quite favorable and published in a peer-reviewed medical journal.
How it works
Formula C™ is a specific blend of medicinal grade hemp flower terpenes and phytocannabinoids in a suspension of coconut oil designed to support the proper function of the Endocannabinoid System, the system that regulates homeostasis at the cellular level throughout the body.
The Endocannabinoid System influences both inflammation and pain.
Terpenes and Phytocannabinoids are bioactive natural products with medicinal properties.
Terpenes contain psychoactive properties that relax the nervous system while they elevate mood and alertness. They can also ward off pathogens/infectious diseases. They are also used in anti-dementia (memory-enhancing) drugs to enhance cholinergic activity.
Phytocannabinoids can be beneficial for ailments such as pain, anxiety, and cachexia - a “wasting” disorder that causes extreme weight loss and muscle wasting.
Improvement in common Long COVID symptoms and quality of life have been observed when adding Formula C™ to Long COVID treatment protocols.
CCG followers participated in the Phase 4 Clinical Trial, and we have been following Formula C development since 2021.
Formula C is a 100% plant-based formulation designed by Michael Steward MD, an RNA virus specialist, to assist people with chronic COVID symptoms.
The thesis, which was published in another peer reviewed medical journal, proposes that one of the main body systems impacted by acute COVID is the Endocannabinoid system (ECS).
If you are curious about the Endocannabinoid system (which exists in every human and animal on the planet), the following videos explain how COVID can impact this system in your body and how Formula C can help bring it back into alignment.
The Endocannabinoid System
The Endocannabinoid system is the largest collection of neurotransmitters in the body, brain, central and immune system, and the primary regulator of most primary bodily functions including: Immune cells, motor activity, thinking, cardiovascular and central nervous system (CNS). It is the system specifically dedicated to maintaining homeostasis of the body.
Study Results
Acute COVID knocks the endocannabinoid system out of whack, potentially negatively impacting the functioning of other systems. Restoring the ECS to proper function can significantly improve Long COVID symptoms. To test the thesis the study tracked 9 of the most common Long COVID symptoms to see if Formula C through the ECS could aid patient recovery. In the published results, Formula C improved all 9 symptoms over the first 28 days and 8 of 9 by day 56. Patient overall quality of life was also tracked and doubled in the first 28 days and tripled by day 56. There was not one significant adverse event in the trial.
How was quality of life measured in the clinical trials?
Patient Global Impression of Change (PGIC)
Participants completed the Patient Global Impression of Change (PGIC), a common tool that measures how participants observe their own response to a therapy or their impression of their own improvement or suffering. Once questions are all answered, a score is assigned for each response. In the Formula C clinical trials, participants showed improved scores at the end of the trial, compared to the starting scores.
Formula C information
The primary active ingredients in Formula C are hemp derived terpenes. Terpenes are the natural aroma molecules that give all plants their smell. Hemp terpenes are unique and have a significant impact on the endocannabinoid system. There are over 200 known terpenes and each of them has a different physiological impact on the body so combining the correct terpenes together is essential to create an effective product.
The terpenes in Formula C were specifically chosen to align with symptoms typical of Long COVID patients. In addition to terpenes Formula C does have trace amounts of THC and CBD, so they are not intoxicating. If you may be tested at work for either, you will want to check with your HR department before starting.
The hemp components in Formula C are Federally legal in the United States and Formula C may be used in any state without a prescription.
We reached out to the company behind Formula C and we were able to secure a discount for our CCG followers. Furthermore, the company has generously pledged to donate 20% of member sales to CCG to help support our community.
We are acutely aware of the exhaustion our community faces while experimenting with numerous treatments without finding relief, therefore, we negotiated with the company to also offer our members a 30-day money-back guarantee should you decide to purchase the product and find it falls short of your expectations.
How to take Formula C:
Place the sublingual drops under the tongue and hold them there for 60-90 seconds. For maximum absorption, hold food and drink for 15 minutes before and after taking.
If you have any tolerance issues or feel drowsy, reduce the amount.
In this video, a long COVID doctor discusses dosing:
Using the recommended dosing for one month takes about 2 bottles. Most people will stay on for 3 to 4 months before titrating back down to 0.25 mL twice per day following the same schedule in reverse.
Click here for a Formula C one-pager with full dosage instructions.
Most health savings account (HSA) plans will allow you to purchase Formula C on your plan. Simply use your savings plan card at time of purchase. If you need to submit a form, ask your existing health care provider or reach out to ProMedView to request a consultation.
Opting for a one-time purchase provides a 40% discount, while choosing automatic refills provides a 50% discount and you can cancel at any time. Considering that CCG followers have experienced optimal benefits from using the product for 60 to 90 days, the automatic refill option will help to sustain progress and save you some money.
You can purchase Formula C through our link below using most healthcare savings plans:
The company is offering CCG followers a 30-day money back guarantee if it isn’t helping.
Long COVID Support
If you need additional support for your Long COVID recovery or symptom management, you can find support with a Nurse Coach through ProMedView. Request information on services and pricing HERE.
Formula C FAQs
What is the back story behind Formula C?
Learn about the Formula C story by watching these two brief videos:
What is Formula C?
Formula C is a therapeutic taken sublingually that was developed and researched to address the leading symptoms of Long COVID.
Symptoms that were studied include anxiety, depression, fatigue, sleep disturbance, pain, dyspnea, cognitive function, participation in social activity and satisfaction with social activity.
Where does Formula C come from?
Formula C was created by a biotech firm called Endourage specifically for Long COVID research.
Formula C was tested for safety and efficacy in an IRB-approved Phase 4 Long COVID Human Trial.
The trial is posted on www.clinicaltrials.gov, and published in a peer-reviewed journal.
Does Formula C help relieve Long COVID symptoms?
The trial showed Formula C improved 9 of 9 symptoms the first 28 days of the trial and improved 8 of 9 symptoms through 56 days (the 9th symptom of pain was not an issue for participants in the last 4 weeks).
The trial showed Formula C is safe.
No significant adverse effects occurred.
Participants reported their quality of life improved using a Patient Global Impression of Change (PGIC) scale.
Clinicians at hospitals and clinics recommending Formula C for Long COVID in 2023 report their observations are consistent with the published research findings.
What does Formula C do?
It targets the Endocannabinoid System, which regulates homeostasis at the cellular level throughout the body by producing human cannabinoids.
Research suggests that Long COVID symptoms are due in part to an impaired Endocannabinoid System.
Formula C introduces a specific formulation of plant cannabinoids, called phytocannabinoids, that uniquely support the stressed Endocannabinoid System.
Is Formula C a prescription drug?
No, Formula C is a 100% natural, hemp-derived therapeutic that may be obtained without a prescription.
What are the active ingredients in Formula C?
Formula C is a therapeutic derived from hemp, which contains ~400 active ingredients spanning cannabinoids, flavonoids and terpenes.
Active ingredients are listed on the Formula C label, including beta-caryophyllene, cannabigerol, cannabidiol, myrcene, and less than .3% delta-9 tetrahydrocannabinol.
Does Formula C have significant adverse effects?
No significant adverse effects have been reported by clinicians or clinical trial researchers.
Mild-modest grogginess has resolved by lowering the dose.
Can Formula C make you high?
Formula C is not intoxicating and non-habit forming because it has a low TCH concentration.
Can anyone with Long COVID symptoms take Formula C?
As Formula C has only been studied in adults, it is only recommended for adult use.
People that work for employers with incompatible policies where phytocannabinoids are concerned should resolve with employers before use.
Why are we hearing about Formula C now?
The research was completed and published in 2022, and 2023 was spent with specific Post Covid Care Center physicians evaluating Formula C to prepare for broader 2024 launch.
Does Formula C work for everyone?
It works for most people, but not all.
Published research and clinician observations show it is safe for all, effective for many, and brings no significant adverse side effects.
How is Formula C dosed?
General dosing instructions are included with each shipment of Formula C.
Is Formula C covered by insurance plans?
Not currently, as it is too new and requires a unique review process as a non-drug therapeutic.
Formula C™ is also covered by most health savings accounts (HSA). HSA cards can be used to place an order.
Consumers referred by ProMedView and covidCAREgroup will receive discount pricing.
What about allergies?
Those allergic to coconut or hemp should not take Formula C.
Why is there a breastfeeding and pregnancy warning on the label?
Formula C was researched with adults only who were not pregnant or breastfeeding, therefore it is only recommended for adults who are not breastfeeding or pregnant, until further research is able to advise otherwise.
Why is there a California www.P65warnings.ca.gov notice on the label?
To comply with a California-Only State Regulation pertaining to disclosure of activities or product categories that may result in some exposure to any of more than 900 chemicals on a regulated list.
Delta 9 tetrahydrocannabinol is listed and found in full-spectrum hemp in safe, non-intoxicating trace amounts (<3%) in complete compliance with the 2018 U.S. Farm Bill.
Should Formula C be kept in a dim, cool place?
Yes, most people store Formula C in the refrigerator ideally, or at room temperature in a dim place (e.g. cabinet, drawer, cupboard, pantry).
Heat degrades Formula C. Those living in a warm climate will want to retrieve Formula C from the mailbox or doorstep promptly when it arrives.
How is Formula C taken?
Place the Formula C dropper under tongue and expunge Formula C. Remove the empty dropper from tongue.
For 60 seconds let Formula C keep mouth closed and tongue relaxed on bottom of mouth while Formula C is absorbed into the blood stream under the tongue.
Avoid swallowing before the drops are held under the tongue, as the digestive system will break down the active components of Formula C before they is absorbed to the blood stream. Swallowing Formula C is safe.
40%-50% automatic savings applied when purchasing Formula C through this CCG link.
Advanced clinical trial in progress
When you purchase Formula C you will receive an email inviting you to participate in the new advanced clinical trial evaluating the efficacy of Formula C in reducing Long COVID symptoms including brain fog, anxiety, depression and fatigue.
Now seeking participants 21 and older for the 90-day advanced Formula C™ study, in which participants will answer weekly surveys to track symptoms and wellbeing.
FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE
This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use if you have a serious medical condition or use prescription medications. A Doctor’s advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are property of their respective owners and not affiliated with or do they endorse this product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Individual weight loss results will vary. By using this site you agree to follow the Privacy Policy and all Terms & Conditions printed on this site. Void where prohibited by law.
Information provided by Endourage, committed to finding natural solutions for Long COVID and good health.
Endourage is founded, managed, and advised by medical doctors, research scientists, and operators that focus on developing hemp-derived, indication-specific formulations for clinical use.